Histiocytosis X of the vulva with a confusing clinical and pathologic presentation. A case report.

Abstract

Histiocytosis X (HX) is a rare disorder of Langerhans cells and most commonly occurs in children. We report a case of HX of the vulva in a 76-year-old woman that clinically simulated a yeast infection of the vulva but histologically resembled an amelanotic melanoma. We briefly report the clinical and pathologic features of this case, which responded to vincristine followed by vinblastine and was in complete remission after nine months.

• Authors: V Savell, R Hanna, J A Benda, Z B Argenyi
• Journal: The Journal of reproductive medicine (J Reprod Med) Vol. 40 Issue 4 Pg. 323-6 (Apr 1995) ISSN: 0024-7758 [Print] United States
• PMID: 7623365 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Diagnosis, Differential
• Female
• Histiocytosis, Langerhans-Cell (pathology)
• Humans
• Melanoma, Amelanotic (pathology)
• Mycoses (pathology)
• Vulvar Diseases (pathology)
• Vulvar Neoplasms (pathology)