[A trial of clinical application of sparfloxacin for treating mycobacterial infections].

Abstract

Sparfloxacin seems to be a good candidate for antimycobacterial treatment. However, there have been no clinical studies. We experienced 2 SPFX-treated cases, who could not use other antimycobacterial agents because of side effect, we tried SPFX-treatment on these cases. Good results were obtained, however, for long time use to prevent side effects, we tried SPFX every second day and monitored the serum levels of SPFX. SPFX-every second day treatment gave good clinical results and adequate serum levels of SPFX were observed.

• Authors: H Yoshikawa, N Aoki, Y Usuda, K Wada, M Arakawa
• Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases (Kansenshogaku Zasshi) Vol. 69 Issue 7 Pg. 818-25 (Jul 1995) ISSN: 0387-5911 [Print] Japan
• PMID: 7561253 (Publication Type: Case Reports, Clinical Trial, English Abstract, Journal Article)

Chemical References

• Fluoroquinolones
• Quinolones
• sparfloxacin

Topics

• Aged
• Aged, 80 and over
• Female
• Fluoroquinolones
• Humans
• Male
• Middle Aged
• Mycobacterium Infections (drug therapy)
• Quinolones (administration & dosage)