[Treatment of pharmacotoxic psychoses with clopenthixol in patients with Parkinson's disease (author's transl)].

Abstract

Pharmacotoxic psychoses resulting from therapy of advanced Parkinson's disease can occur in up to 60% of the patients. Treatment must not be completely discontinued in such cases. Clopenthixol (Sordinol, Ciatyl) in small dosage has been shown to be much more effective than all other types of therapy in the management of those psychoses. In a group of 28 patients treated with clopenthixol the progression of Parkinson's disease was not quicker than a control group of 30 patients not treated with clopenthixol. Both groups were of similar age and at a similar stage of the disease.

• Authors: W Danielczyk
• Journal: Wiener klinische Wochenschrift (Wien Klin Wochenschr) Vol. 93 Issue 15 Pg. 500-1 (Aug 07 1981) ISSN: 0043-5325 [Print] Austria
• Vernacular Title: Die Behandlung von pharmakotoxischen Psychosen bei Parkinson-Patienten mit Clopenthixol.
• PMID: 7303692 (Publication Type: Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Antiparkinson Agents
• Thioxanthenes
• Clopenthixol

Topics

• Antiparkinson Agents (adverse effects, therapeutic use)
• Clopenthixol (therapeutic use)
• Dose-Response Relationship, Drug
• Humans
• Parkinson Disease (drug therapy)
• Psychoses, Substance-Induced (drug therapy)
• Thioxanthenes (therapeutic use)