Transcobalamin-binding capacities in vitamin B12-related diseases.

Abstract

Abnormalities in some transcobalamin unsaturated binding capacities (TC-UBBC) were found in some patients with treated pernicious anemia who had elevated TC II-UBBC, R-UBBC, and total UBBC, in gastrectomized patients with latent vitamin B12 deficiency who had elevated R-UBBC and UBBC, and in patients with obstructive jaundice who had elevated TC II-UBBC and UBBC. No abnormalities were found in patients who had untreated pernicious anemia, folate deficiency, unclassifiable megaloblastic anemia, tobacco amblyopia, or low serum B12 level but normal capacity to absorb vitamin B12.

• Authors: C MacDonald, R Bessent, J Adams
• Journal: American journal of clinical pathology (Am J Clin Pathol) Vol. 75 Issue 5 Pg. 677-83 (May 1981) ISSN: 0002-9173 [Print] England
• PMID: 7234754 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)

Chemical References

• Blood Proteins
• Transcobalamins
• Vitamin B 12

Topics

• Anemia, Pernicious (metabolism)
• Biliary Tract Diseases (metabolism)
• Blood Proteins (metabolism)
• Female
• Humans
• Liver Diseases (metabolism)
• Male
• Sex Factors
• Transcobalamins (metabolism)
• Vitamin B 12 (metabolism)
• Vitamin B 12 Deficiency (metabolism)