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Hydroxyethyl starch-induced macroamylasemia.

Abstract
Summarizing, the following results were obtained: 1. After infusion of 500 ml hydroxyethyl starch 6% in all patients an increase of serum amylase occurred, which in most cases reached values twice as high as the basal value. 2. This hyperamylasemia is caused by the formation of a high molecular HES-amylase complex, which cannot be easily eliminated. 3. In no case was hyperamylasemia associated with other clinical signs or symptoms.
AuthorsH Köhler, W Kirch, H J Horstmann
JournalInternational journal of clinical pharmacology and biopharmacy (Int J Clin Pharmacol Biopharm) Vol. 15 Issue 9 Pg. 428-31 (Sep 1977) ISSN: 0340-0026 [Print] Germany
PMID72048 (Publication Type: Journal Article)
Chemical References
  • Hydroxyethyl Starch Derivatives
  • Starch
  • Amylases
Topics
  • Amylases (blood, urine)
  • Chromatography, Gel
  • Humans
  • Hydroxyethyl Starch Derivatives (adverse effects)
  • Pancreas (drug effects)
  • Starch (analogs & derivatives)
  • Time Factors

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