[Clinical study of PC-904 in pediatrics (author's transl)].

Abstract

Clinical study of PC-904 was performed in 8 children with infectious diseases and the following results were obtained. 1) The patients treated with PC-904 were each one case of acute pharyngitis, lacunar tonsillitis, scarlet fever, phlegmone, acute bronchitis and lung abscess, and 2 cases of bronchopneumonia. 2) The administration methods were drip infusion, one-shot intravenous injection and the combined use of these administrations. The daily dosage varied from 30 to 49 mg/kg in 3 cases and from 50 to 70 mg/kg in 3 cases, and was 227 mg/kg in 1 case. 3) Clinical evaluation was examined in 7 cases and 57.1% of effectiveness was obtained. Out of 2 cases of pneumonia, one case with the causative organism of My. pneumoniae was excluded from the clinical evaluation. 4) No side effects were observed in all 8 cases treated with PC-904.

• Authors: M Minamitani, K Hachimori
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 31 Issue 7 Pg. 383-8 (Jul 1978) ISSN: 0368-2781 [Print] Japan
• PMID: 691262 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Naphthyridines
• Ampicillin

Topics

• Age Factors
• Ampicillin (administration & dosage, adverse effects, analogs & derivatives, therapeutic use)
• Bacterial Infections (blood, drug therapy)
• Child
• Child, Preschool
• Drug Evaluation
• Female
• Humans
• Infant
• Injections, Intravenous
• Male
• Naphthyridines (administration & dosage, adverse effects, therapeutic use)