[Experiences with intranasal and parenteral use of 1-desamino-8-D-arginine vasopressin (DDAVP). Use in the diagnosis of hypophyseal function].

Abstract

While 1-desamino-8-D-arginine-vasopressin is not suitable for the functional diagnostics of the anterior pituitary gland, it has as in the therapy of the central diabetes insipidus a firm place also in its diagnostics. A hypothalamic neurohypophyseal system was demonstrated. Apart from a secure diagnostic evidence the test shows further advantages in comparison to the hitherto performed methods: an essentially smaller load for patient and personnel, a shorter duration and a simplified performance. First findings in patients with central diabetes insipidus, in a female patient with renal diabetes insipidus and patient without disturbance of the water balance are discussed. A control of our findings in other institutions is desirable.

• Authors: U Tuschy, S Szeszat, J Meinhold
• Journal: Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete (Z Gesamte Inn Med) Vol. 38 Issue 17 Pg. 475-7 (Sep 01 1983) ISSN: 0044-2542 [Print] Germany
• Vernacular Title: Erfahrungen bei der intranasalen und parenteralen Anwendung von 1-Desamino-8-D-Arginin-Vasopressin (DDAVP). Anwendung in der Hypophysenfuktionsdiagnostik.
• PMID: 6636917 (Publication Type: English Abstract, Journal Article)

Chemical References

• Arginine Vasopressin
• Deamino Arginine Vasopressin

Topics

• Administration, Intranasal
• Arginine Vasopressin
• Deamino Arginine Vasopressin
• Diabetes Insipidus (diagnosis)
• Humans
• Injections, Intravenous
• Kidney Concentrating Ability (drug effects)
• Pituitary Function Tests (methods)
• Water-Electrolyte Balance (drug effects)