The influence of
methandrostenolone (=
Dianabol = 17-beta-hydroxy-17-methylandrosta-1,4-dien-3-one) and of a running training program on the degradation rate of myofibrillar
proteins of the heart, soleus, red portion of the vastus lateralis, and white portion of the vastus lateralis of female guinea pigs was studied by measuring the time-dependent decrease of radioactive-labeled
proteins. The following results were obtained: No alteration of absolute muscle or
body weight An increased heart-to-
body weight relation in the trained and in the trained group receiving
Dianabol A significantly higher myofibrillar
protein concentration in the skeletal muscle types than in the heart An increased concentration of myofibrillar
proteins in all muscle types in the trained group receiving
Dianabol and in the heart of the untrained group receiving
Dianabol The degradation rate of the myofibrillar
proteins decreased in all muscle types in the trained group receiving
Dianabol and in the heart of the untrained group receiving
Dianabol and in the trained group.