Abstract |
At a disturbed synaptic transmission in the rabbit cranial sympathetic cervical ganglion in histological sections stained with gallocyanin chrome alum, distribution of the chromatophilic substance was studied, and in the same sections RNA content was determined cytophotometrically. In ganglia of intact animals three groups of neurons with various structure of the chromatophilic substance were defined and their quantitative relation was stated. After administration of various doses of the ganglio-blockader, there was an essential difference in the changes of the chromatophilic substance, but they were unitypical in mono- and double-nuclear neurons. In the same cells, the synaptic blockade produced a rather great increase in the content of the cytoplasmic RNA. Comparing the quantitative data with the visual observation results, a conclusion was made that it is not reliable to use any changes in the chromatophilic substance as a criterium on quantitative shifts in the neuronal RNA and for the morphological test of the neuronal functional activity.
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Authors | P L Gorelikov |
Journal | Arkhiv anatomii, gistologii i embriologii
(Arkh Anat Gistol Embriol)
Vol. 81
Issue 7
Pg. 58-64
(Jul 1981)
ISSN: 0004-1947 [Print] Russia (Federation) |
Vernacular Title | Funktsional'nye izmeneniia khromatofil'nogo veshchestva i soderzhaniia RNK v tsitoplazme simpaticheskikh neĭronov pri narushenii sinapticheskoĭ peredachi. |
PMID | 6170279
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Pipecolic Acids
- dimecolin
- RNA
|
Topics |
- Animals
- Autonomic Nerve Block
- Chinchilla
- Ganglia, Sympathetic
(metabolism)
- Histocytochemistry
- Pipecolic Acids
(administration & dosage)
- RNA
(metabolism)
- Rabbits
- Synaptic Transmission
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