Acute parotitis and hyperamylasemia following whole-brain radiation therapy.

Abstract

Parotitis, an infrequent, previously unreported complication of whole-brain radiation therapy, was observed in 4 patients. The acute symptoms, which include fever, dry mouth, pain, swelling, and tenderness, are accompanied by hyperamylasemia. Among 10 patients receiving whole-brain irradiation, 8 had serum amylase elevations without symptoms. Both acute parotitis and asymptomatic hyperamylasemia result from irradiation of the parotid glands.

• Authors: J G Cairncross, J Salmon, J H Kim, J B Posner
• Journal: Annals of neurology (Ann Neurol) Vol. 7 Issue 4 Pg. 385-7 (Apr 1980) ISSN: 0364-5134 [Print] United States
• PMID: 6155101 (Publication Type: Case Reports, Journal Article)

Chemical References

• Amylases

Topics

• Adult
• Amylases (blood)
• Brain Neoplasms (radiotherapy, secondary)
• Cerebellar Neoplasms (radiotherapy, secondary)
• Female
• Humans
• Male
• Meningeal Neoplasms (radiotherapy)
• Middle Aged
• Parotid Gland (radiation effects)
• Parotitis (diagnosis, etiology)
• Radiation Injuries (diagnosis, etiology)
• Radiotherapy (adverse effects)