Episiotomy pain: efficacy and safety of fluproquazone compared to aspirin and placebo.

Abstract

The analgesic efficacy of fluproquazone at 100 mg and 200 mg doses, was measured in 160 patients with episiotomy pain and was compared to that of aspirin (650 mg) and placebo. The 100-mg dose of fluproquazone was more effective in relieving episiotomy pain than the 200-mg dose of fluproquazone, aspirin or placebo in terms of mean pain intensity scores after 1 h. All active compounds were more effective than placebo by all criteria.

• Authors: R London, G S Sundaram, S Feldman, P Goldstein
• Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (Int J Gynaecol Obstet) Vol. 21 Issue 3 Pg. 251-5 (Jun 1983) ISSN: 0020-7292 [Print] United States
• PMID: 6139316 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Quinazolines
• Quinazolinones
• Aspirin
• fluproquazone

Topics

• Adolescent
• Adult
• Anti-Inflammatory Agents, Non-Steroidal (administration & dosage)
• Aspirin (administration & dosage)
• Clinical Trials as Topic
• Dose-Response Relationship, Drug
• Double-Blind Method
• Episiotomy
• Female
• Humans
• Pain, Postoperative (drug therapy)
• Prospective Studies
• Quinazolines (administration & dosage)
• Quinazolinones
• Random Allocation