[Danger of iodine drugs in the pregnant woman].

Abstract

The authors draw attention to the fact that the possible effects of drugs containing iodine are often neglected during pregnancy. As an example, they report the following observation : "A young woman with benign asthma, treated for 14 years Asthmasedine and Asthmaligne, gave birth, on the 36th week of pregnancy, to a child apparenty dead but who was able to be reanimated. The child showed two types of signs : respiratory distress due to higher neurological disorders and a multinodular, non-compressing goiter. These two complications were caused by a congenital hypothyroidism corroborated by laboratory tests and due to the prolonged absorption of iodinated drugs by the mother". In conclusion, in cases of women receiving during pregnancy high doses of drugs containing iodine (250 such drugs are recorded in the Vidal), it is desirable to control the effect on the fetus and to propose an intra-amniotic therapy with L-Thyroxine, thus allowing a cerebral development close to normal.

• Authors: G Crepin, G Delahousse, J Decocq, M Delcroix, F Caquant, D Querleu, L Taleb
• Journal: Phlebologie (Phlebologie) 1978 Jul-Sep Vol. 31 Issue 3 Pg. 279-85 ISSN: 0031-8280 [Print] France
• Vernacular Title: Dangers des médicaments iodés chez la femme enceinte.
• PMID: 581616 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Potassium Iodide
• Iodine

Topics

• Adult
• Asthma (drug therapy)
• Congenital Hypothyroidism
• Female
• Goiter, Nodular (chemically induced, congenital)
• Humans
• Hypothyroidism (chemically induced)
• Infant, Newborn
• Iodine (adverse effects, metabolism)
• Maternal-Fetal Exchange
• Potassium Iodide (adverse effects, therapeutic use)
• Pregnancy
• Pregnancy Complications (drug therapy)
• Respiratory Distress Syndrome, Newborn (etiology)