Abstract |
10 healthy men received an i.v. infusion of maltose at a dosage of 1.5 g/kg/h over a period of 1 h. No clinical side effects were observed. Total protein and albumin showed a significant drop. The glucose level remained constant. The concentration of maltose rose up to 495 +/- 77 mg/100 ml. The osmo- diuretic action of the solution was proven by a renal excretion of 289 +/- 57 ml water/h, 14.6 g maltose/h and 3.9 g glucose/h. The total carbohydrate elimination was 61.8 +/- 9.1 g/8 h, (44.5 +/- 13.5 maltose and 15.7 [+8.1--21,2] glucose). The specific action of maltose is an induction of glucosuria without hyperglycemia.
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Authors | G Berg, F Matzkies, R Kellner |
Journal | Arzneimittel-Forschung
(Arzneimittelforschung)
Vol. 27
Issue 11
Pg. 2174-6
( 1977)
ISSN: 0004-4172 [Print] Germany |
Vernacular Title | Maltose als Substrat zur Induktion einer osmotischen Diurese. |
PMID | 580025
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Blood Glucose
- Diuretics, Osmotic
- Maltose
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Topics |
- Adult
- Blood Glucose
(metabolism)
- Diuretics, Osmotic
- Glycosuria
(chemically induced)
- Humans
- Male
- Maltose
(pharmacology)
- Time Factors
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