[Progressive External Ophthalmoplegia (authors transl)].

Abstract

The case of a 16-year-old boy with progressive external ophthalmoplegia ("Ophthalmoplegia plus") is reported. Clinical symptoms consisted of complete external ophthalmoplegia, ptosis, short stature, atrophy and weakness of skeletal muscles, and elevated csf protein. Abnormal mitochondria were found by electron microscopy in scattered atrophic fibres of the muscle biopsy. The syndrome and it's relevance for paediatric differential diagnosis is discussed.

• Authors: M Gabriel, H G Lenard, H H Goebel
• Journal: Klinische Padiatrie (Klin Padiatr) Vol. 190 Issue 5 Pg. 441-5 (Sep 1978) ISSN: 0300-8630 [Print] Germany
• Vernacular Title: Die progressive externe Ophthalmoplegie.
• PMID: 568196 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Cerebrospinal Fluid Proteins

Topics

• Adolescent
• Biopsy
• Blepharoptosis (complications)
• Cerebrospinal Fluid Proteins (analysis)
• Dwarfism (complications)
• Humans
• Male
• Mitochondria, Muscle (ultrastructure)
• Muscles (pathology)
• Muscular Atrophy (complications)
• Ophthalmoplegia (cerebrospinal fluid, complications, diagnosis, pathology)