Bleomycin in testicular teratomas.

Abstract

Bleomycin and its combinations have a definite place in the treatment of metastatic testicular carcinomas other than seminomas and may also prove to be effective, when given as adjuvant postoperative therapy in state II disease. A study, using the combination of Bleomycin and CCNU in 17 patients with metastatic testicular teratoma, is reported. A remission rate of 59% has been observed. Only patients with a complete remission had a satisfactory remission duration. Sequential combinations, using all drugs effective in this disease, may be the most promising way to further improve therapeutic results in terms of remission rate and survival.

• Authors: K W Brunner, R W Sonntag
• Journal: Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology (Z Krebsforsch Klin Onkol Cancer Res Clin Oncol) Vol. 84 Issue 3 Pg. 291-7 (Nov 25 1975) ISSN: 0084-5353 [Print] Germany
• PMID: 53948 (Publication Type: Journal Article)

Chemical References

• Bleomycin
• Vincristine
• Lomustine

Topics

• Adult
• Bleomycin (therapeutic use)
• Choriocarcinoma (drug therapy)
• Drug Therapy, Combination
• Follow-Up Studies
• Humans
• Lomustine (therapeutic use)
• Lung Neoplasms (drug therapy)
• Male
• Neoplasm Metastasis
• Remission, Spontaneous
• Teratoma (drug therapy)
• Testicular Neoplasms (drug therapy)
• Vincristine (therapeutic use)