Abstract |
A two and one-half year old boy with complex congenital heart disease had Howell-Jolly bodies in his blood raising the possibility of the asplenia syndrome. A 99mTc-sulfur colloid liver-spleen scan was reported normal, but the right lobe of the abnormally reversed liver was mistaken for the spleen. The diagnosis of visceral heterotaxy (Ivemark's syndrome) was established after scanning the patient with a new radiopharmaceutical, 99mTechnetium pyridoxylidene glutamate. The agent clearly demonstrated a left-sided gall bladder, and on comparison with the sulfur colloid scan it was established that asplenia was present. Radionuclide imaging with the new generation of hepatobiliary agents is a reliable method to document asplenia and is useful in studying patients with visceral heterotaxy.
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Authors | B Pastakia, L M Lieberman, D Moodie, J Levy |
Journal | Gastroenterology
(Gastroenterology)
Vol. 77
Issue 5
Pg. 1105-8
(Nov 1979)
ISSN: 0016-5085 [Print] United States |
PMID | 488637
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Glutamates
- pyridoxylideneglutamate
- Pyridoxal
- Technetium
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Topics |
- Child, Preschool
- Gallbladder
(abnormalities)
- Glutamates
- Heart Atria
(diagnostic imaging)
- Heart Defects, Congenital
(diagnostic imaging)
- Heart Septal Defects, Ventricular
(diagnostic imaging)
- Humans
- Liver
(abnormalities)
- Male
- Pyridoxal
(analogs & derivatives)
- Radionuclide Imaging
- Situs Inversus
(diagnostic imaging)
- Spleen
(abnormalities, diagnostic imaging)
- Syndrome
- Technetium
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