Immunological assessment of sera of leprosy patients.

Abstract

IgG levels were significantly high in sera of all types of leprosy. House-hold contacts of lepromatous leprosy (LL) cases also showed significantly higher values for IgG when compared to that of control. Except polar tuberculoid (TT) cases and house-hold contacts other types of leprosy revealed a significant rise in IgA levels in their sera. IgM was only raised in borderline tuberculoid (BT) cases. C-reactive protein (CRP) was present in the sera of all types of leprosy. Highest positivity (97%) was shown by sera from erythema nodosum leprosum (ENL) cases. Rose-Waaler antibody (RA) was noted in BT, borderline leprosy (BL), LL and ENL cases. Significance of these findings is discussed.

• Authors: U Sengupta, S Sinha, G Ramu
• Journal: Leprosy in India (Lepr India) Vol. 51 Issue 1 Pg. 43-8 (Jan 1979) ISSN: 0024-1024 [Print] India
• PMID: 449283 (Publication Type: Journal Article)

Chemical References

• Immunoglobulin A
• Immunoglobulin G
• Immunoglobulin M
• C-Reactive Protein

Topics

• C-Reactive Protein (immunology)
• Humans
• Immunoglobulin A (immunology)
• Immunoglobulin G (immunology)
• Immunoglobulin M (immunology)
• Leprosy (blood, immunology)