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Selective inhibition of dopamine-beta-hydroxylase in the peripheral tissues by 5-dimethyldithiocarbamylpicolinic acid; its effect on stress-induced ulcer, ethanol-induced sleep and blood pressure.

AuthorsH Hidaka, F Hara, N Harada, Y Hashizume, M Yano
JournalThe Journal of pharmacology and experimental therapeutics (J Pharmacol Exp Ther) Vol. 191 Issue 3 Pg. 384-92 (Dec 1974) ISSN: 0022-3565 [Print] United States
PMID4473535 (Publication Type: Journal Article)
Chemical References
  • Carbamates
  • Picolinic Acids
  • Tritium
  • Ethanol
  • 5-dimethyldithiocarbamylpicolinic acid
  • Reserpine
  • Dopamine beta-Hydroxylase
  • Dopamine
  • Norepinephrine
Topics
  • Adrenal Glands (enzymology)
  • Animals
  • Blood Pressure (drug effects)
  • Brain (metabolism)
  • Carbamates (pharmacology, therapeutic use)
  • Cattle
  • Dopamine (metabolism)
  • Dopamine beta-Hydroxylase (antagonists & inhibitors)
  • Ethanol (pharmacology)
  • Humans
  • Male
  • Mice
  • Myocardium (metabolism)
  • Norepinephrine (biosynthesis)
  • Picolinic Acids (pharmacology, therapeutic use)
  • Rats
  • Reserpine (pharmacology)
  • Sleep (drug effects)
  • Stomach Ulcer (etiology, physiopathology, prevention & control)
  • Stress, Psychological
  • Time Factors
  • Tritium

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