[Clinical studies on aspoxicillin in the pediatric field].

Abstract

Studies on efficacy and safety of aspoxicillin (ASPC) were carried out to 14 cases of pediatric infections, and the following results were obtained. Clinical efficacy of ASPC to 10 respiratory infections, 1 urinary tract infection and 1 otitis media was excellent in 6 cases (50%) and good in 6 cases (50%). The efficacy rate was 100%. Bacteriological effect of ASPC to 6 cases which detected the causative organisms (S. aureus, E. faecalis, H. influenzae and P. mirabilis) was eliminate in 3 cases (50%) and replace in 3 cases (50%). The bacterial eliminated rate was 100%. Side effects of ASPC to 14 administered cases were observed in 2 cases, that were urticaria in 1 case and elevation of GOT in 1 case. From the above results, it was concluded that ASPC was the useful and secure antibiotic drug for treatment of infections in pediatric field.

• Authors: H Nagao, K Kida, H Matsuda, M Murase
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 38 Issue 7 Pg. 1918-24 (Jul 1985) ISSN: 0368-2781 [Print] Japan
• PMID: 4068225 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• aspoxicillin
• Amoxicillin

Topics

• Amoxicillin (administration & dosage, adverse effects, analogs & derivatives, therapeutic use)
• Bacteria (isolation & purification)
• Bacterial Infections (drug therapy, microbiology)
• Child
• Child, Preschool
• Drug Evaluation
• Female
• Humans
• Infant
• Injections, Intravenous
• Male
• Otitis Media (drug therapy)
• Respiratory Tract Infections (drug therapy)
• Urinary Tract Infections (drug therapy)