Detection of incompletely sialylated human chorionic gonadotropin by peanut agglutinin in choriocarcinoma.

Abstract	Human chorionic gonadotropin (hCG) in normal pregnancy and hydatidiform mole did not bind to the peanut agglutinin (PNA)-Sepharose column, whereas significant amount of hCG in choriocarcinoma adsorbed to the column. Therefore, PNA-Sepharose affinity chromatography is an effective tool for the detection of desialylated hCG and may be useful also for the diagnosis of choriocarcinoma.
Authors	R Nishimura, T Mizuochi, T Utsunomiya, K Ide, A Kobata, M Mochizuki
Journal	The Japanese journal of experimental medicine (Jpn J Exp Med) Vol. 55 Issue 2 Pg. 75-8 (Apr 1985) ISSN: 0021-5031 [Print] Japan
PMID	4046212 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Chorionic Gonadotropin Lectins Macromolecular Substances Peanut Agglutinin Plant Lectins Sialic Acids
Topics	Arachis Choriocarcinoma (analysis) Chorionic Gonadotropin (analysis) Female Humans Hydatidiform Mole (analysis) Lectins Macromolecular Substances Peanut Agglutinin Plant Lectins Pregnancy Sialic Acids (analysis) Uterine Neoplasms (analysis)

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