[Bornaprine in the treatment of parkinsonian tremor].

Abstract

We report the results of a double-blind placebo controlled study of bornaprine, an anticholinergic drug, in the treatment of Parkinson's disease. We studied 17 patients presenting persistent tremor in spite of a stable long-term L-Dopa therapy. The bornaprine, in doses of 8 mg/die, compared with placebo significantly improves tremor. Only mild side effects occurred. We think the bornaprine may be of value in the treatment of parkinsonian tremor.

• Authors: M Piccirilli, P D'Alessandro, A Testa, G L Piccinin, L Agostini
• Journal: Rivista di neurologia (Riv Neurol) 1985 Jan-Feb Vol. 55 Issue 1 Pg. 38-45 ISSN: 0035-6344 [Print] Italy
• Vernacular Title: Il bornaprine nel trattamento del tremore parkinsoniano.
• PMID: 3895365 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Antiparkinson Agents
• Bridged-Ring Compounds
• bornaprine

Topics

• Antiparkinson Agents (therapeutic use)
• Bridged-Ring Compounds (adverse effects, therapeutic use)
• Clinical Trials as Topic
• Double-Blind Method
• Female
• Humans
• Male
• Middle Aged
• Parkinson Disease (drug therapy)
• Vision Disorders (chemically induced)