Abstract | INTRODUCTION: METHODS: We performed a cross-sectional learn about with 9443 contributors the usage of 2007-2018 NHANES data. Multiple logistic regression evaluation has been utilized to check out the affiliation of dietary vitamin C intake with NAFLD and advanced hepatic fibrosis (AHF). Subsequently, we plotted a smoothed match curve to visualize the association. Especially, the analysis of AHF was conducted among the NAFLD population. In addition, stratified evaluation used to be developed primarily based on demographic variables to verify the steadiness of the results. Effect amendment by way of dietary potassium intake used to be assessed via interplay checks between vitamin C and NAFLD in the multivariable linear regression. RESULTS: In this cross-sectional study, we found that vitamin C was negatively related to NAFLD and AHF. The relationship between vitamin C and NAFLD was different in the low, middle and high potassium intake groups. Furthermore, potassium intake significantly modified the negative relationship between vitamin C and NAFLD in most of the models. CONCLUSION: Our research showed that potassium and vitamin C have an interactive effect in reducing NAFLD, which may have great importance for clinical medication.
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Authors | Xu-Hua Liu, Hao-Kai Chen, Jing Luo, Xiang-Ping He, Wan-Lin Zhang, Yue Chen, Xiu-Juan Li, Qi-Wen Lan, Xiao-Man Ma, Xu-Guang Guo |
Journal | PloS one
(PLoS One)
Vol. 19
Issue 4
Pg. e0295986
( 2024)
ISSN: 1932-6203 [Electronic] United States |
PMID | 38635545
(Publication Type: Journal Article)
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Copyright | Copyright: © 2024 Liu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
Chemical References |
- Ascorbic Acid
- Potassium
- Potassium, Dietary
- Vitamins
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Topics |
- Adult
- Humans
- United States
(epidemiology)
- Non-alcoholic Fatty Liver Disease
(epidemiology)
- Ascorbic Acid
- Cross-Sectional Studies
- Nutrition Surveys
- Potassium
- Potassium, Dietary
- Vitamins
- Eating
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