Magnetostrictive-piezocatalytic CoFe2O4@UiO-66 nanohybrid and its potential for deep-seated tumor treatment.

Abstract

Magnetostrictive CoFe2O4 (CFO) nanoparticles were encapsulated within a UiO-66 metal-organic-framework layer to form a CFO@UiO-66 nanohybrid. The deforming of CFO, in response to a high-frequency AC magnetic field, initiates the piezocatalytic property of UiO-66 to generate ˙OH radicals, which can kill cancer cells buried in thick tissues, showcasing bright potential for deep-seated tumor treatment.

• Authors: Qian Yu, Meiyu Li, Jiaojiao Zhang, Hong Liu, Long Zhang, Shun Li, Dengfeng Ge, Jianming Zhang
• Journal: Chemical communications (Cambridge, England) (Chem Commun (Camb)) Vol. 60 Issue 33 Pg. 4463-4466 (Apr 18 2024) ISSN: 1364-548X [Electronic] England
• PMID: 38563776 (Publication Type: Journal Article)

Chemical References

• UiO-66
• Metal-Organic Frameworks
• Phthalic Acids

Topics

• Humans
• Metal-Organic Frameworks
• Neoplasms
• Phthalic Acids
• Magnetic Fields