Abstract | BACKGROUND: METHODS: The study analyzed the clinicopathologic findings and surgical outcomes of 988 patients with radiologic, ground-glass opacity-dominant non-small cell lung cancer without lymph node involvement who underwent complete resection of the primary tumor between 2010 and 2020. Patients were followed up for 54.5 months (median). Kaplan-Meier curves and the log-rank test were used in statistical analyses of the prognosis. RESULTS: Median age, whole tumor size, solid tumor size, and maximum standardized uptake values were 68 years, 1.7 cm, 0.4 cm, and 0.9, respectively. Sixty percent of the cohort was female (n = 590). Wedge resection, segmentectomy, and lobectomy were performed in 206, 372, and 410 patients, respectively. A total of 982 of 988 (99%) tumors were adenocarcinomas. One patient had hilar lymph node involvement; however, no mediastinal lymph node metastasis or hilar or mediastinal lymph node recurrence was detected. The 5-year overall survival rate was 96.5% (95% CI, 94.8%-97.7%). Excellent survival outcomes were achieved regardless of procedure (wedge resection, 94.7% [95% CI, 89.1%-97.5%]; segmentectomy, 96.9% [95% CI, 93.7%-98.5%]; and lobectomy, 97.1% [95% CI, 94.4%-98.5%]). CONCLUSIONS:
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Authors | Takahiro Mimae, Yoshihiro Miyata, Norifumi Tsubokawa, Yujin Kudo, Takuya Nagashima, Hiroyuki Ito, Norihiko Ikeda, Morihito Okada |
Journal | The Annals of thoracic surgery
(Ann Thorac Surg)
(Mar 19 2024)
ISSN: 1552-6259 [Electronic] Netherlands |
PMID | 38513985
(Publication Type: Journal Article)
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Copyright | Copyright © 2024 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved. |