DESIGN: Prospective Cross-sectional study.
SETTING: We retrospectively interrogated the Qatar
Stroke Database in all patients admitted between 2014-2022 with
acute ischemic stroke and evaluated the relationship between
triglyceride, diabetes,
stroke severity (measured on NIHSS),
stroke type (TOAST classification) and the short- (mRS at 90 days) and long-term outcomes (
MACE at 1 year) in patients with HT.
PARTICIPANTS: Six thousand five hundred fifty-eight patients ≥20 years were included in this study RESULTS: Six thousand five hundred fifty-eight patients with
ischemic stroke [mean age 54.6 ± 12. 9; male 82.1%) were included.
Triglyceride levels upon admission were low-normal (≤1.1 mmol/L) in 2019 patients, high-normal (1.2-1.7 mmol/L) in 2142 patients, borderline-high (1.8-2.2 mmol/L) in 1072 patients and high (≥2.3 mmol/L) in 1325 patients. Higher
triglyceride levels were associated with
stroke and increased likelihood of having diabetes,
obesity, active smoking, and small vessel/
lacunar stroke type. An inverse relationship was noted whereby higher
triglyceride levels were associated with lower
stroke severity and reduced likelihood of poorer outcome (mRS 3-6) at discharge and 90 days. Long-term
MACE events were less frequent in patients with higher
triglyceride levels. After adjusting age, gender, diabetes, prior
stroke, CAD, and
obesity, multivariate analysis showed that
hypertension and
triglyceride levels were higher in mild
ischemic strokes patients.
CONCLUSIONS: