Centrality angle is a novel nephrometry score to predict tumor complexity and perioperative outcomes for partial nephrectomy.

Abstract

To propose the centrality angle (C-angle) as a novel simple nephrometry score for the evaluation of tumor complexity and prediction of perioperative outcomes in nephron-sparing surgery (NSS) for renal tumors. The analysis was based on 174 patients who underwent robot-assisted partial nephrectomy retrospectively. C-angle was defined as the angle occupied by the tumor from the center of the kidney in the coronal CT images. Other nephrometry scores were calculated and compared with C-angle. Associations between C-angle and perioperative outcomes were examined. Significant differences were found in C-angle between tumors greater and less than 4 cm, exophytic and endophytic tumors, and hilar and non-hilar tumors. C-angle was correlated with other nephrometry scores, including RENAL, PADUA, and C-index. Significant positive correlations with WIT, operation time, and EBL, and significant negative correlations with preserved eGFR. C-angle could predict perioperative complications. Patients with a C-angle > 45° had worse perioperative outcomes, including longer operative time, longer WIT, lower rate of preserved eGFR, and complications. C-angle can be used to evaluate the complexity of renal tumors and predict perioperative outcomes. C-angle can potentially be used for decision-making in the treatment of patients and to guide surgical planning of NSS.

• Authors: Shunsuke Miyamoto, Keisuke Goto, Ryo Tasaka, Yuki Kohada, Takafumi Fukushima, Kenshiro Takemoto, Takashi Babasaki, Kohei Kobatake, Yohei Sekino, Hiroyuki Kitano, Kenichiro Ikeda, Keisuke Hieda, Tetsutaro Hayashi, Nobuyuki Hinata
• Journal: Scientific reports (Sci Rep) Vol. 14 Issue 1 Pg. 4780 (02 27 2024) ISSN: 2045-2322 [Electronic] England
• PMID: 38413713 (Publication Type: Journal Article)
• Copyright: © 2024. The Author(s).

Topics

• Humans
• Retrospective Studies
• Glomerular Filtration Rate
• Nephrectomy (adverse effects)
• Kidney (diagnostic imaging, surgery, pathology)
• Kidney Neoplasms (diagnostic imaging, surgery, etiology)
• Treatment Outcome