A 75-year-old female, at her initial presentation, the
tumor occupied her entire right breast, with a foul-smelling exudate. A biopsy revealed ER-positive, HER2-negative
breast cancer, and CT revealed multiple lung
metastases.
Paclitaxel and
fulvestrant were administered sequentially, the
bleeding from the right breast mass stopped and the mass flattened. But, as the
tumor progressed, the right breast mass re-enlarged and began to re-bleed. Therefore,
hemostatic treatment with
Mohs paste was performed in parallel with
tamoxifen.
Hemostatic effect was observed for a while, but she gradually became refractory to
Mohs paste, necessitating frequent
blood transfusions. It was decided to discontinue systemic
drug therapy and consider
palliative treatment, and to perform
radiation therapy in parallel with
Mohs paste treatment for the purpose of local control. After
radiation therapy, the
bleeding has completely stopped and
blood transfusion has not to be required for 6 months. Although systemic
drug therapy has been discontinued at the patient's request, she is still alive. While systemic
drug therapy was discontinued, we were able to confirm the pure local control effect of combination of
radiation therapy and
Mohs paste.