A comprehensive overview of post-stroke depression treatment options.

Abstract

Nearly one-third of all stroke patients develop depression at any time after a stroke, and its presence is associated with unfavorable outcomes. This narrative review aims to provide a synopsis of possible pharmacological and non-pharmacological treatment modalities for post-stroke depression (PSD). Several studies have demonstrated the efficacy and safety of selective serotonin reuptake inhibitors in treating the symptoms of this clinical condition. The treatment of PSD has been recently enhanced by innovative approaches, such as cognitive-behavioral therapy, virtual reality, telehealth, repetitive transcranial magnetic stimulation, and non-conventional therapies, which might improve depression treatment in stroke survivors. Future high-quality randomized controlled trials are necessary to confirm this hypothesis.

• Authors: Alberto Raggi, Alessandro Serretti, Raffaele Ferri
• Journal: International clinical psychopharmacology (Int Clin Psychopharmacol) Vol. 39 Issue 3 Pg. 127-138 (May 01 2024) ISSN: 1473-5857 [Electronic] England
• PMID: 38170802 (Publication Type: Review, Journal Article)
• Copyright: Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Chemical References

• Selective Serotonin Reuptake Inhibitors

Topics

• Humans
• Depression (etiology, therapy, diagnosis)
• Stroke (complications, therapy)
• Selective Serotonin Reuptake Inhibitors