Tubular aggregate myopathy causing progressive fatiguable weakness.

Abstract

Tubular aggregate myopathies comprise a rare group of disorders with characteristic pathological findings and heterogeneous phenotypes, including myasthenic syndrome. We describe a patient with tubular aggregate myopathy who presented with fatiguable weakness improving with pyridostigmine, respiratory involvement and possible cardiac manifestations. We highlight the utility of muscle biopsy in atypical myasthenic syndrome.

• Authors: Qihua Fan, Kelly Gwathmey, Xinli Du, Arjun Seth, Andrea Corse
• Journal: Practical neurology (Pract Neurol) (Nov 03 2023) ISSN: 1474-7766 [Electronic] England
• PMID: 37923376 (Publication Type: Journal Article)
• Copyright: © Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.