Intra-nasal flunisolide in the treatment of allergic rhinitis in general practice.

Abstract

An open trial was carried out in general practice to assess the effectiveness and acceptability of flunisolide nasal spray in relieving symptoms of allergic rhinitis. Eighty-eight patients were entered in the study, 82 of whom were hay fever sufferers. The spray was given as 2 insufflations into each nostril, using a metered pump, twice daily over a period of 1 month. This provided a daily dose of 200 microgram flunisolide. Patients' symptoms were assessed on entry and at 2-week intervals. Flunisolide produced statistically significant reductions in all symptoms and resulted in complete or good control in 73 patients.

• Authors: C I Backhouse
• Journal: Current medical research and opinion (Curr Med Res Opin) Vol. 6 Issue 1 Pg. 14-9 ( 1979) ISSN: 0300-7995 [Print] England
• PMID: 378554 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Aerosols
• Fluocinolone Acetonide

Topics

• Administration, Intranasal
• Adolescent
• Adult
• Aerosols
• Aged
• Child
• Clinical Trials as Topic
• Family Practice
• Female
• Fluocinolone Acetonide (administration & dosage, adverse effects, analogs & derivatives, therapeutic use)
• Humans
• Male
• Middle Aged
• Pollen
• Rhinitis, Allergic, Seasonal (drug therapy)
• Time Factors