Case Report: Hematoporphyrin Injection (HpD) Photodynamic Therapy for the Treatment of Groin Extramammary Paget's Disease in an Elderly Male Patient.

Abstract

Hematoporphyrin Derivative-Photodynamic Therapy (HpD-PDT) is a promising modality for cancer treatment, particularly suitable for challenging sites or elderly patients who can benefit from its minimally invasive and selective nature. We report a case of groin extramammary Paget's disease (EMPD) in a male patient with a lesion located in the right mons pubis. The patient was deemed unsuitable for surgical treatment due to his advanced age, underlying health conditions, extensive rash area, and the specific location of the groin lesion. He opted for hematoporphyrin photodynamic therapy instead of traditional wide local excision. The tumors were successfully treated, with no recurrence observed during the follow-up period. We suggest that hematoporphyrin photodynamic therapy may be an effective alternative to conventional surgery for the treatment of extramammary Paget's disease.

• Authors: Xiaoqing Xiang, Yanliang Li, Xiguang Liu, Guozhang Ma
• Journal: Photodiagnosis and photodynamic therapy (Photodiagnosis Photodyn Ther) Pg. 103727 (Jul 31 2023) ISSN: 1873-1597 [Electronic] Netherlands
• PMID: 37797911 (Publication Type: Case Reports)
• Copyright: Copyright © 2023. Published by Elsevier B.V.