Vaccination is an evidence-based strategy to prevent or reduce the severity of
infectious diseases (ID). Here, we aimed to describe the experience of implementing a vaccination clinic specifically targeting liver, heart, lung, and combined dual
organ transplantation at a single
transplantation center in Denmark. In this cohort of 242 solid organ transplant (SOT) candidates, we investigated seroprotection and the proportion of recommended vaccinations documented before
transplantation. Furthermore, we registered completed vaccinations after ID consultations. The median age in our cohort was 53 years (IQR, 42-60), 60% were males (n = 135), and
liver transplants (n = 138; 57%) were the most frequently planned organ transplants. Before the consultation to the vaccination clinic,
influenza and
pneumococcal vaccines had the highest proportion of documented vaccination (58% and 37%, respectively). Serological protection was more frequently observed for
measles,
mumps, or
rubella (MMR, approximately 90% for each), while only 30% (n = 72) of SOT candidates showed seroprotection against
pneumococcal disease. All SOT candidates required at least one of the recommended
vaccines, and over 90% required three or more. At least 10% of patients in our cohort needed a live
attenuated vaccine for either MMR or
yellow fever. The most frequently administered
vaccine was the
tetanus-
diphtheria-acelullar
pertussis (Tdap) booster (n = 217; 90%),
influenza vaccination was either administered (n = 16; 7%) or recommended (n = 226; 93%), PCV13 was administered (n = 155; 64%) or recommended (n = 27; 11%), and
PPSV23 was either administered (n = 18; 7.4%) or recommended (n = 140; 58%). All SOT candidates adhered completely to their vaccination schedules. Based on our findings, we recommend prioritizing vaccination before
transplantation by providing ID consultations for SOT candidates.