Prevalence and Trends of Birth Defects - Five Counties, Shanxi Province, China, 2003-2022.

Abstract

What is already known about this topic?:

The Shanxi Province, located in northern China, holds the highest prevalence of birth defects (BDs) across the country. Following the implementation of a nationwide folic acid supplementation program in 2009, a significant reduction of 53.89% in the prevalence of neural tube defects (NTDs) was observed in Shanxi from 2012 to 2017. However, despite this decrease, the prevalence rate for congenital heart defects (CHDs) in 2017 was over four times that of the 2012 rate. Since 2014, CHDs have emerged as the most predominant BD in Shanxi.

What is added by this report?:

The present study has identified a marked reduction in the prevalence of both total BDs and NTDs in five counties within Shanxi over the past two decades. As of 2017-2022, NTDs continue to be the most prevalent BDs recorded in this region. Contrarily, there has been a noteworthy increase in the prevalence of CHDs, ranking them among the top five most common BDs in the region between 2017 and 2022, though their rate remains below the national average. Additionally, the proportion of external anomalies remains high. Nevertheless, due to constrained access to primary healthcare services and diagnostic facilities, the early detection rate for internal anomalies, particularly CHDs, may be underestimated in the region.

What are the implications for public health practice?:

The results of this study underscore the necessity for augmented efforts in promoting folic acid supplementation as a preventive measure for NTDs. Moreover, improvements in the distribution of medical resources within this region are recommended, particularly the introduction and enforcement of local training programs aimed at enhancing CHD screening and diagnostic processes in these respective counties.

• Authors: Duoduo Wang, Zhijiao Song, Yali Zhang, Le Zhang, Lei Jin, Aiguo Ren, Zhiwen Li, Jufen Liu
• Journal: China CDC weekly (China CDC Wkly) Vol. 5 Issue 36 Pg. 797-802 (Sep 08 2023) ISSN: 2096-7071 [Electronic] China
• PMID: 37771624 (Publication Type: Journal Article)
• Copyright: Copyright and License information: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2023.