Abstract | PURPOSE: METHODS: An analytical cross-sectional study. RESULTS: In total, 14.57% of eyes with FKH progressed to endophthalmitis. Hypopyon, pre-existence of lens problems, topical steroid use and sever keratitis were significantly associated with the development of FKE. The risk factors of the FKH and FE group were mainly plant trauma and open globe trauma, respectively. Keratitis-related endophthalmitis (FKE) showed a significantly higher resistance than the other two groups. The FKH group had the best final visual acuity, while the FKE group had the worst. CONCLUSION: Hypopyon height, pre-existing lens problems, topical steroid use and sever keratitis are risk factors for progression to endophthalmitis in eyes with fungal keratitis, and its progression is not affected by a single fungus. The antifungal drugs resistance in patients with endophthalmitis related to keratitis was significantly higher than that associated with other reasons. Timely diagnosis and risk factor assessment are essential for ensuring early treatment of FKE.
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Authors | Yu Sun, Fanxing Zeng, Jingjing Zhang, Xiaolin Qi, Xiuhai Lu, Na Ning, Suxia Li, Ting Zhang, Gongqiang Yuan, Weiyun Shi, Hua Gao |
Journal | Mycopathologia
(Mycopathologia)
Vol. 188
Issue 5
Pg. 805-813
(Oct 2023)
ISSN: 1573-0832 [Electronic] Netherlands |
PMID | 37737909
(Publication Type: Journal Article)
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Copyright | © 2023. The Author(s), under exclusive licence to Springer Nature B.V. |