Multisystem Inflammatory Syndrome in Children Among Persons Who Completed a Two-dose COVID-19 Vaccine Primary Series Compared With Those Reporting No COVID-19 Vaccination, US National MIS-C Surveillance.

Abstract

We analyzed multisystem inflammatory syndrome in children cases by reported COVID-19 vaccination status (2-dose primary series vs. no vaccination). A total of 46% vaccinated versus 58% unvaccinated persons received intensive care unit-level care ( P = 0.02); the risk of intensive care unit admission was 23% higher (adjusted relative risk: 1.23; 95% confidence interval: 1.03-1.48) among unvaccinated patients; 21 unvaccinated persons died. Multisystem inflammatory syndrome in children occurs after SARS-CoV-2 infection in vaccinated persons, but may be less severe.

• Authors: Anna R Yousaf, Allison D Miller, Katherine Lindsey, Ami B Shah, Michael J Wu, Michael Melgar, Laura D Zambrano, Angela P Campbell
• Journal: The Pediatric infectious disease journal (Pediatr Infect Dis J) Vol. 42 Issue 12 Pg. e476-e478 (12 01 2023) ISSN: 1532-0987 [Electronic] United States
• PMID: 37725819 (Publication Type: Journal Article)
• Copyright: Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Chemical References

• COVID-19 Vaccines

Topics

• Child
• Humans
• COVID-19 Vaccines
• COVID-19 (epidemiology, prevention & control)
• SARS-CoV-2
• Vaccination