Extrinsic lipoid pneumonia due to chronic polyethylene glycol consumption: A case report.

Abstract

Extrinsic lipoid pneumonia (ELP) results from the aspiration of lipid-containing substances. Tissue or cell histopathology after Oil-Red-O staining can confirm the diagnosis, which requires proper tissue handling and preparation during bronchoscopy. Here, we report a case of ELP in a quadriplegic patient with a long history of dysphagia and polyethylene glycol consumption. Computed tomography (CT) of the chest revealed multiple, progressively enlarging, fat-attenuated, nodular pulmonary lesions. Bronchoscopy with bronchoalveolar lavage (BAL) and a transbronchial forceps biopsy confirmed the diagnosis of lipoid pneumonia. We discuss the clinical, radiological, and pathological features of ELP and highlight the preparatory steps required for obtaining a successful diagnosis.

• Authors: Robert J Murphy, Steven Tessier, Santo Longo, Christopher S Alia, Firas Ido
• Journal: Respiratory investigation (Respir Investig) Vol. 61 Issue 6 Pg. 768-772 (Nov 2023) ISSN: 2212-5353 [Electronic] Netherlands
• PMID: 37716285 (Publication Type: Case Reports)
• Copyright: Copyright © 2023 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.

Chemical References

• Polyethylene Glycols
• Mineral Oil

Topics

• Humans
• Pneumonia, Lipid (chemically induced, diagnostic imaging)
• Polyethylene Glycols (adverse effects)
• Mineral Oil
• Bronchoalveolar Lavage (methods)
• Lung (pathology)