Enlarging 18 F-FDG-Avid Solitary Pulmonary Nodule: A Distinctly Unusual Presentation of Cytomegalovirus Infection in a Patient Receiving Chemotherapy.

Abstract

ABSTRACT:

Rapidly growing lung lesions, particularly in immunocompromised patients, invoke consideration of an infectious etiology. Aspergillomas, for example, can appear as round nodules with soft tissue attenuation, often associated with cavitation, and are variably 18 F-FDG avid. In contrast, cytomegalovirus, which may also evidence 18 F-FDG uptake, typically manifests as ground-glass opacities, symmetrically distributed small pulmonary nodules, or confluent consolidations, with lower lobe predilection. We describe a patient treated for lymphoma presenting with a solitary enlarging FDG-avid lung nodule, which was determined on resection to be focal cytomegalovirus infection, a distinctly uncommon presentation of this pathogen, more typical of fungal or mycobacterial disease.

• Authors: Edgar Zamora, Ukuemi Edema, Lionel S Zuckier
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 48 Issue 10 Pg. 917-918 (Oct 01 2023) ISSN: 1536-0229 [Electronic] United States
• PMID: 37656604 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Chemical References

• Fluorodeoxyglucose F18
• abamectin

Topics

• Humans
• Solitary Pulmonary Nodule (diagnostic imaging)
• Fluorodeoxyglucose F18
• Cytomegalovirus Infections (complications, diagnostic imaging)
• Biological Transport