Abstract | OBJECTIVE: Pituitary abscess is an often misdiagnosed, rare clinical disorder. To improve diagnostic accuracy and the efficacy of surgical and antibiotic therapy for patients with pituitary abscess, herein, we retrospectively reviewed 15 patients who presented with pituitary abscesses from 2005 to 2022. DESIGN: Retrospective study. PATIENTS: Fifteen patients underwent transsphenoidal surgery and received antibiotic treatment. MEASUREMENTS: Complete details regarding medical history, clinical manifestations, laboratory examinations, imaging studies, and treatment strategies were obtained for all patients. RESULTS: CONCLUSIONS: The typical manifestations of pituitary abscess include hypopituitarism and headaches; the presence of an enhanced ring at the edge of the mass on contrast-enhanced magnetic resonance images (MRI) is highly suggestive of pituitary abscess. We recommend antibiotic treatment for 4-6 weeks postoperatively, based on the results of bacterial cultures or metagenomic next-generation sequencing (mNGS).
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Authors | Bing-Bo Zhuang, Jing Chen, Qiang Zhang, Guo-Liang Zhang, Song-Sheng Shi |
Journal | Neuro-Chirurgie
(Neurochirurgie)
Vol. 69
Issue 5
Pg. 101478
(Sep 2023)
ISSN: 1773-0619 [Electronic] France |
PMID | 37598621
(Publication Type: Journal Article)
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Copyright | Copyright © 2023 Elsevier Masson SAS. All rights reserved. |