Abstract | BACKGROUND: The contribution of insulin to acne is that it stimulates the synthesis of androgenic hormones, which are important in the development of excess sebum, hyperkeratinization, and sebaceous gland cell growth. OBJECTIVE: METHODS: An analytical cross-sectional study with case-control design research investigation of 72 individuals with acne vulgaris and 72 healthy volunteers was carried out. Both groups' medical histories were taken, as were the severity and duration of the disease among acne sufferers, as well as demographic data. Anthropometry tests were performed on both groups, including their weights, height, and circumference of waist, as well as the profile of lipids, blood glucose levels after a fast, insulin levels during fasting, resistance to insulin, and Apo B-48 folding change. RESULTS: CONCLUSION:
|
Authors | Ahmed Ibrahim AbdElneam, Mohammed Saleh Al-Dhubaibi, Saleh Salem Bahaj, Ghada Farouk Mohammed, Lina Mohamed Atef |
Journal | Gene
(Gene)
Vol. 885
Pg. 147703
(Nov 15 2023)
ISSN: 1879-0038 [Electronic] Netherlands |
PMID | 37572798
(Publication Type: Journal Article)
|
Copyright | Copyright © 2023 Elsevier B.V. All rights reserved. |
Chemical References |
- Apolipoprotein B-48
- Blood Glucose
- Insulin
- Cholesterol, LDL
|
Topics |
- Humans
- Insulin Resistance
(genetics)
- Apolipoprotein B-48
- Blood Glucose
(metabolism)
- Cross-Sectional Studies
- Insulin
- Acne Vulgaris
(genetics)
- Cholesterol, LDL
- Gene Expression
|