Abstract |
Materials and Methods: Thirty adult male Wistar rats were randomly divided into six groups (n=5 per group): group of nondiabetic rats as a negative control (group 1); untreated diabetic rats (group 2); diabetic rats treated with DLBS3233 4.5 mg/kg BB (group 3); 9 mg/kg BB (group 4); 18 mg/kg BB (group 5); and diabetic rats treated with pioglitazone (group 6). The authors checked Homeostatic Model Assessment for Insulin Resistance to corroborate insulin resistance prior to DLBS3233 administration in diabetic rats. Immunohistochemistry was performed to examine the expression of renal antimalondialdehyde (MDA) antibodies, nephrin, podocin, and insulin receptor serine. The data were analyzed using analysis of variance and the t-test. Result: Conclusion:
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Authors | Chandra I Mohani, Achmad Rudijanto, Aulanni'am Aulanni'am, Setyawati Soeharto |
Journal | Annals of medicine and surgery (2012)
(Ann Med Surg (Lond))
Vol. 85
Issue 8
Pg. 3894-3900
(Aug 2023)
ISSN: 2049-0801 [Print] England |
PMID | 37554909
(Publication Type: Journal Article)
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Copyright | Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. |