Abstract | INTRODUCTION:
Infectious mononucleosis (IM) is a common infectious disease in children mainly caused by Epstein-Barr virus ( EBV) infection, followed by abnormal immune response, and resulting in serious complications. However, there are few clinical analyses of immune responses in children with IM at different stages. METHODS: This study combined EBV serological test and EBV DNA test to diagnose the infection status of children with IM, and the infection status was divided into primary acute IM infection (AIM), primary late IM infection (LIM) and reactivation IM infection (RIM). RESULTS: CONCLUSION: There are differences in immune response at different stages of infection, which can provide guidance for effective treatment in children with IM infection.
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Authors | Bing Chen, Ning Han, Ling-Yu Gao, Ting-Dong Zhou, Hao Zhang, Pei He, Qiang Zhou |
Journal | International journal of laboratory hematology
(Int J Lab Hematol)
Vol. 45
Issue 6
Pg. 890-898
(Dec 2023)
ISSN: 1751-553X [Electronic] England |
PMID | 37501513
(Publication Type: Journal Article)
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Copyright | © 2023 John Wiley & Sons Ltd. |
Chemical References |
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Topics |
- Child
- Humans
- Infectious Mononucleosis
(diagnosis)
- Herpesvirus 4, Human
- Epstein-Barr Virus Infections
(complications, diagnosis)
- Latent Infection
- DNA
- Immunity
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