We present the consensus document on the immunization schedule for adolescents developed by 3 scientific societies: the Spanish Association of Pediatrics (AEP), through its Advisory Committee on
Vaccines (CAV-AEP), the Spanish Society of Adolescent Medicine (SEMA) and the Spanish Association of Vaccinology (AEV). There are particularities in
infectious disease during adolescence, such as an increased susceptibility to
pertussis, poorer outcomes of
chickenpox,
mumps and
hepatitis A, a high incidence of
sexually transmitted infections or increased prevalence of meningococcal carriage. The document analyses the schedule for adolescents in the context of vaccination policy overall. It contemplates the
vaccines to be included in the immunization schedule for healthy adolescents: against invasive
meningococcal disease (tetravalent ACWY and B), against human papillomavirus (which should be gender-neutral), against
pertussis, against
influenza and against SARS-CoV-2 (in unvaccinated individuals and at-risk groups). It is worth noting that the
4CMenB vaccine appears to confer some protection against gonococcal
infection, which would be a considerable added value for adolescents. The vaccination of adolescents belonging to risk groups or travelling abroad also needs to be contemplated, as is the case in any other age group. Vaccination against
hepatitis A, which is included in the routine immunization schedule of Catalonia, Ceuta and Melilla from the second year of life, should also be considered a priority in adolescents traveling to endemic areas.