Intrarenal small artery thrombosis in a transplant recipient patient infected with Covid-19 after kidney transplantation: A rare case report.

Abstract

Currently, renal arteriovenous thrombosis induced by Covid-19 infection in patients after renal transplantation is very rare. We present a recent kidney transplant recipient who developed Covid-19 infection and later developed intrarenal small artery thrombosis. Finally, the patient's respiratory tract infection symptoms gradually disappeared after treatment. However, hemodialysis replacement therapy has to be continued due to the injury of the transplanted kidney function. In this case, we first reported that Covid-19 infection may induce intrarenal small artery thrombosis after kidney transplantation, which caused local ischemic necrosis of the transplanted kidney. We found that patients are at a high risk of Covid-19 infection at the early stage after kidney transplantation, and their clinical symptoms may be severe. In addition, even with anticoagulant therapy, Covid-19 infection may still increase the risk of thrombosis to some extent for patients who have undergone kidney transplantation, and we need to be alert to this rare complication in the future clinical work.

• Authors: Yan Liu, Gen Chen, Zhenhua Liu, Xiangang Xu, Shengpeng Yang, Yong Shi, Zetao Zhao, Bo Wang, Yi Zhang
• Journal: Transplant immunology (Transpl Immunol) Vol. 80 Pg. 101886 (10 2023) ISSN: 1878-5492 [Electronic] Netherlands
• PMID: 37422093 (Publication Type: Case Reports, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2023 Elsevier B.V. All rights reserved.

Topics

• Humans
• Kidney Transplantation (adverse effects)
• COVID-19
• Transplant Recipients
• Kidney Diseases
• Thrombosis (etiology)
• Arteries