Abstract | INTRODUCTION: AREAS COVERED: EXPERT OPINION: A pragmatic, adaptive, randomized, multicenter phase II/III study evaluating vilobelimab for the treatment of severe COVID-19 found that patients receiving invasive mechanical ventilation and usual care who were treated with vilobelimab had a lower risk of death by day 28 and day 60 compared to those receiving placebo. This manuscript explores what is known about vilobelimab and explores how this treatment may be used in the future to treat severe COVID-19.
|
Authors | Matthew W McCarthy |
Journal | Expert opinion on biological therapy
(Expert Opin Biol Ther)
2023 Jul-Dec
Vol. 23
Issue 9
Pg. 877-881
ISSN: 1744-7682 [Electronic] England |
PMID | 37421632
(Publication Type: Clinical Trial, Phase II, Clinical Trial, Phase III, Journal Article, Multicenter Study, Pragmatic Clinical Trial, Randomized Controlled Trial)
|
Chemical References |
- Antibodies, Monoclonal
- vilobelimab
|
Topics |
- Adult
- Animals
- Humans
- Mice
- Antibodies, Monoclonal
- COVID-19
- Inflammation
- Respiration, Artificial
- SARS-CoV-2
- United States
|