Influence of device-assisted suction against resistance (Mueller maneuver) on image quality in CTPA for suspected lung embolism.

Abstract

OBJECTIVES:

To investigate the effect of a device-assisted suction against resistance Mueller maneuver (MM) on transient interruption of contrast (TIC) in the aorta and pulmonary trunk (PT) on computed tomography pulmonary angiogram (CTPA).

METHODS:

In this prospective single-center study, 150 patients with suspected pulmonary artery embolism were assigned randomly with two different breathing maneuvers (Mueller maneuver (MM) or standard end-inspiratory breath-hold command (SBC)) during routine CTPA. The MM was performed using a patented prototype (Contrast Booster™) which allows both the patient by means of visual feedback and the medical staff in the CT scanning room to monitor whether the patient is sucking sufficiently or not. Mean Hounsfield attenuation in descending aorta and PT was measured and compared.

RESULTS:

Overall, patients with MM showed an attenuation of 338.24 HU in the pulmonary trunk, compared to 313.71 HU in SBC (p = 0.157). In the aorta, the values for MM were lower compared to SBC (134.42 HU vs. 177.83 HU, p = 0.001). The TP-aortic ratio was significantly higher in the MM group at 3.86 compared to the SBC group at 2.26, p = 0.001. TIC phenomenon was absent in the MM group, whereas it was present in 9 patients (12.3%) in the SBC group (p = 0.005). Overall contrast was better on all levels for MM (p < 0.001). The presence of breathing artifacts was higher in the MM group (48.1% vs. 30.1%, p = 0.038), without clinical consequence.

CONCLUSIONS:

Performing the MM with the application of the prototype is an effective way of preventing the TIC phenomenon during i.v. contrast-enhanced CTPA scanning compared to the standard end-inspiratory breathing command.

CLINICAL RELEVANCE:

Compared to standard end-inspiratory breathing command, the device-assisted Mueller maneuver (MM) improves contrast enhancement and prevents the transient interruption of contrast (TIC) phenomenon in CTPA. Therefore, it may offer optimized diagnostic workup and timely treatment for patients with pulmonary embolism.

KEY POINTS:

• Transient interruption of contrast (TIC) may impair image quality in CTPA. • Mueller Maneuver using a device prototype could lower the rate of TIC. • Device application in clinical routine may increase diagnostic accuracy.

• Authors: Niklas von Münchhausen, Sonja Janssen, Daniel Overhoff, Johann S Rink, Bram Geurts, Andreas Gutzeit, Mathias Prokop, Stefan O Schoenberg, Matthias F Froelich
• Journal: European radiology (Eur Radiol) Vol. 33 Issue 11 Pg. 7840-7848 (Nov 2023) ISSN: 1432-1084 [Electronic] Germany
• PMID: 37338555 (Publication Type: Randomized Controlled Trial, Journal Article)
• Copyright: © 2023. The Author(s).

Chemical References

• Contrast Media

Topics

• Humans
• Suction
• Prospective Studies
• Tomography, X-Ray Computed (methods)
• Pulmonary Artery (diagnostic imaging)
• Pulmonary Embolism (diagnostic imaging)
• Lung (diagnostic imaging)
• Contrast Media