Platelet-activating factor as an endogenous cofactor of food anaphylaxis.

Abstract

Anaphylaxis is a severe, acute, life-threatening generalized or systemic hypersensitivity reaction. The incidence of anaphylaxis is increasing worldwide, with medications and food contributing to most cases. Physical exercise, acute infections, drugs, alcohol, and menstruation are the external cofactors associated with more severe systemic reaction. The aim of this review is to show that platelet-activating factor contributes to the development of severe anaphylactic reaction, and even to anaphylactic shock.

• Authors: Krzysztof Pałgan, Andrzej Tretyn
• Journal: BioFactors (Oxford, England) (Biofactors) 2023 Sep-Oct Vol. 49 Issue 5 Pg. 976-983 ISSN: 1872-8081 [Electronic] Netherlands
• PMID: 37203358 (Publication Type: Journal Article, Review)
• Copyright: © 2023 The Authors. BioFactors published by Wiley Periodicals LLC on behalf of International Union of Biochemistry and Molecular Biology.