Resistance to Fluconazole of Candida albicans in Vaginal Isolates: a 10-Year Study in a Clinical Referral Center.

Abstract

Review of vaginal isolates of Candida albicans that caused clinical failure in a 10-year collection of vaginal C. albicans specimens obtained in a university vaginitis referral clinic indicated an increase in fluconazole resistance. Factors contributing to azole resistance are discussed, including treatment choice associated with fluconazole-resistant C. albicans vaginal infection.

• Authors: J D Sobel
• Journal: Antimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 67 Issue 5 Pg. e0018123 (05 17 2023) ISSN: 1098-6596 [Electronic] United States
• PMID: 37093005 (Publication Type: Journal Article)

Chemical References

• Fluconazole
• Antifungal Agents

Topics

• Female
• Humans
• Fluconazole (pharmacology, therapeutic use)
• Candida albicans (genetics)
• Antifungal Agents (pharmacology, therapeutic use)
• Microbial Sensitivity Tests
• Vagina
• Vulvovaginitis (drug therapy)
• Drug Resistance, Fungal (genetics)