Abstract | INTRODUCTION:
Osteoporosis leads to more serious consequences in men than in women, but less is known about its impacts on health-related quality of life (HRQoL) of men, and whether the anti- osteoporosis treatment can improve HRQoL of men with osteopenia/osteoprosis. METHODS: RESULTS: A total of 100 men with primary osteoporosis or osteopenia and 100 healthy men were included. The patients were divided into three subgroups: osteopenia (n = 35), osteoporosis (n = 39) and severe osteoporosis (n = 26). Men with osteoporosis or severe osteoporosis had impaired HRQoL in domains of physical health compared to healthy controls. HRQoL scores in physical health related domains of patients with severe osteoporosis were significantly lower compared to healthy controls, and were the poorest among the three subgroups of patients. Fragility fracture history was correlated with lower SF-36 scores about physical health. In 34 men with newly diagnosed osteoporosis receiving bisphosphonates treatment, HRQoL scores were significantly improved in domains of physical health after treatments. CONCLUSIONS:
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Authors | Di-Chen Zhao, Xiao-Yun Lin, Jing Hu, Bing-Na Zhou, Qian Zhang, Ou Wang, Yan Jiang, Wei-Bo Xia, Xiao-Ping Xing, Mei Li |
Journal | BMC musculoskeletal disorders
(BMC Musculoskelet Disord)
Vol. 24
Issue 1
Pg. 309
(Apr 19 2023)
ISSN: 1471-2474 [Electronic] England |
PMID | 37076878
(Publication Type: Journal Article)
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Copyright | © 2023. The Author(s). |
Chemical References |
- Diphosphonates
- Procollagen Type I
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Topics |
- Male
- Humans
- Female
- Diphosphonates
(therapeutic use)
- Quality of Life
- Osteoporosis
(drug therapy)
- Fractures, Bone
- Bone Diseases, Metabolic
(drug therapy)
- Bone Density
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