Abstract | RATIONALE: PATIENT CONCERNS: A 32-year-old woman visited the hospital with premature rupture of membranes at 24 weeks and 4 days of gestation. She was diagnosed with FVII deficiency in an additional blood test after her laboratory results at admission included an increased prothrombin time and international normalized ratio abnormalities. After 12 days of pregnancy maintenance treatment, an emergency cesarean delivery was performed due to uncontrolled preterm labor. The day after the operation, she suffered a sudden loss of consciousness and cardiac arrest, and after she received 1 cycle of cardiopulmonary resuscitation, she was moved to the intensive care unit. DIAGNOSES: INTERVENTIONS: OUTCOMES: There were no major sequelae over 2 months of follow-up. LESSONS: FVII deficiency does not protect against thrombosis. Due to the high thrombotic risk after childbirth, the risk of thrombosis should be recognized, and thromboprophylaxis should be considered if additional obstetric thrombotic risk factors are present.
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Authors | Donghoon Kang, Hojeong Cha, Sung Eun Park, Jong-Hwa Ahn, Ji Kwon Park, Iyun Kwon, Ji Eun Park |
Journal | Medicine
(Medicine (Baltimore))
Vol. 102
Issue 14
Pg. e33437
(Apr 07 2023)
ISSN: 1536-5964 [Electronic] United States |
PMID | 37026947
(Publication Type: Case Reports, Journal Article)
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Copyright | Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. |
Chemical References |
- Anticoagulants
- Factor VII
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Topics |
- Humans
- Pregnancy
- Infant, Newborn
- Female
- Adult
- Factor VII Deficiency
(complications, diagnosis)
- Anticoagulants
(therapeutic use)
- Venous Thromboembolism
(complications)
- Postpartum Period
- Postpartum Hemorrhage
- Pulmonary Embolism
(etiology, complications)
- Thrombosis
(complications)
- Factor VII
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