Progress in vaccine development for infectious diseases-a Keystone Symposia report.

Abstract

The COVID-19 pandemic has taught us many things, among the most important of which is that vaccines are one of the cornerstones of public health that help make modern longevity possible. While several different vaccines have been successful at stemming the morbidity and mortality associated with various infectious diseases, many pathogens/diseases remain recalcitrant to the development of effective vaccination. Recent advances in vaccine technology, immunology, structural biology, and other fields may yet yield insight that will address these diseases; they may also help improve societies' preparedness for future pandemics. On June 1-4, 2022, experts in vaccinology from academia, industry, and government convened for the Keystone symposium "Progress in Vaccine Development for Infectious Diseases" to discuss state-of-the-art technologies, recent advancements in understanding vaccine-mediated immunity, and new aspects of antigen design to aid vaccine effectiveness.

• Authors: Jennifer Cable, Barney S Graham, Richard A Koup, Robert A Seder, Katalin Karikó, Norbert Pardi, Dan H Barouch, Bhawna Sharma, Susanne Rauch, Raffael Nachbagauer, Mattias N E Forsell, Michael Schotsaert, Ali H Ellebedy, Karin Loré, Darrell J Irvine, Emily Pilkington, Siri Tahtinen, Elizabeth A Thompson, Yanis Feraoun, Neil P King, Kevin Saunders, Galit Alter, Syed M Moin, Kwinten Sliepen, Gunilla B Karlsson Hedestam, Hedda Wardemann, Bali Pulendran, Nicole A Doria-Rose, Wan-Ting He, Jennifer A Juno, Sila Ataca, Adam K Wheatley, Jason S McLellan, Laura M Walker, Julia Lederhofer, Lisa C Lindesmith, Holger Wille, Peter J Hotez, Linda-Gail Bekker
• Journal: Annals of the New York Academy of Sciences (Ann N Y Acad Sci) Vol. 1524 Issue 1 Pg. 65-86 (06 2023) ISSN: 1749-6632 [Electronic] United States
• PMID: 37020354 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural)
• Copyright: © 2023 New York Academy of Sciences.

Chemical References

• Vaccines

Topics

• Humans
• Pandemics (prevention & control)
• COVID-19 (prevention & control)
• Vaccines (therapeutic use)
• Communicable Diseases
• Vaccination
• Vaccine Development